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FOLFOX + Avastin for the treatment of Colon Cancer
FOLFOX is the acronym for a chemotherapy regimen used in the treatment of colon cancer.
DRUGS IN THE FOLFOX + AVASTIN COMBINATION:
|
FOL |
= Leucovorin Calcium (Folinic Acid) |
|
F |
|
|
OX |
+ Bevacizumab (Avastin) |
Chemotherapy is often given as a combination of drugs. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.
MOST COMMON SIDE EFFECTS OF FOLFOX + AVASTIN
Risk of Infection
Diarrhea
Mouth Sores
Hand Foot Syndrome
For more information, see the 'Expert Resources' tab below.
Often, the most helpful information regarding treatment side effects comes not from clinical brochures, but rather from other patients like you. We've collected the most helpful community resources to help you prepare for the side effects and coping tips for your chemotherapy regimen.
The following have been voted the 3 most helpful responses to this question.
The main problem for me right now is constipation. It has caused me a lot of discomfort in the anal area from straining to have bm. Does anyone have any suggestions on how to relieve this problem? I’m concerned because it’s like having diaper rash.
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I have had 9 treatments of FloFox with Avasitn and the worst side affect is the neurpathay. I am scheduled for 12 treatments and if the dr is willing I am willing to go as along as I can go before I start maintance of 5-fu for life.
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hey: I’m tolerating this very well. I have very easily managed constipation for the 1st 4 days post chemo and then some diarrhea again easily managed with Imodium. just finished round 6 of 12 bi-weekly & my only issue is low neutrophils. Best of all,my lung tumours are shrinking very well & I can climb stairs & even jog a bit. I notice minor cuts take forever to heal & shaving is a fond memory like my hair…
I’m 62 had adenocarcinoma in 2011 IIIc and got better for 2.5 yrsuntil my CEA went from 1.4 to 33 & my onc jumped on the folfuri with avastin – I doget a shot of atropine before the biweekly chemo along with 2 anti anti nausea meds – but I’ve got no issues.
Sorry to hear that some of you aren’t tolerating this – I don’t think it’s typical.
Diet, exercise & a positive outlook are working for me.
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hey: I’m tolerating this very well. I have very easily managed constipation for the 1st 4 days post chemo and then some diarrhea again easily managed with Imodium. just finished round 6 of 12 bi-weekly & my only issue is low neutrophils. Best of all,my lung tumours are shrinking very well & I can climb stairs & even jog a bit. I notice minor cuts take forever to heal & shaving is a fond memory like my hair…
I’m 62 had adenocarcinoma in 2011 IIIc and got better for 2.5 yrsuntil my CEA went from 1.4 to 33 & my onc jumped on the folfuri with avastin – I doget a shot of atropine before the biweekly chemo along with 2 anti anti nausea meds – but I’ve got no issues.
Sorry to hear that some of you aren’t tolerating this – I don’t think it’s typical.
Diet, exercise & a positive outlook are working for me.
Be first to like this.
Like
I have had 9 treatments of FloFox with Avasitn and the worst side affect is the neurpathay. I am scheduled for 12 treatments and if the dr is willing I am willing to go as along as I can go before I start maintance of 5-fu for life.
Be first to like this.
Like
The main problem for me right now is constipation. It has caused me a lot of discomfort in the anal area from straining to have bm. Does anyone have any suggestions on how to relieve this problem? I’m concerned because it’s like having diaper rash.
Be first to like this.
Like
What were the specific side effects that you experienced while taking this medication? How did you manage them?
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What do you wish you had known before taking this medication? What information would you like to pass on to patients who are beginning this medication?
