I am on Opdivo and have had the joint and muscle pain. So bad that I had to stop for 8 weeks and went on steroids. What amazing relief, however can’t fight the bloody cancer without it. So back on it for the past 4 months. On 10 mg of a steroid, and infusions are every 2 weeks instead of once a month both have made a big difference on my tolerating it so far….
I have been on Opdivo every 30 days for 6 months, immuno therapy trial . Side affects appear to be rash and itchy skin, blotchy skin and join pain (knees, hips and low back. And weakness in the legs. I work out every other day ride a stationary bike hard for 30 minutes, no problem, but walking to my car ,50 yards away ,is difficult.
If you watch the ads on TV for addressing skin problems and arthritis, they warn against other diseases because those drugs work by weakening the immune system. My take , if you are stimulating your immune system to fight cancer, you are likely to cause skin problems and joint pain.
Hopefully when I done in 6 months it will resolve itself but I’m not going to bet the ranch on that. Good luck to all with similar problems.
I’ve been on Opdivo for over 3.5 years. First 2.5 were every 2 weeks, now once a month. I’ve had really no side effects and get full dose. I’ve been on chemotherapy since ‘09, so I’ve been through the list with some effect. Recently had back surgery as a result of the loss of calcium to bones, white hair, and some other side effects. Opdivo so far has been the easiest I’ve had to weather. I have also had radiation and surgery.
I was on Opdivo for a year and developed severe itch and an eczema-like rash. I have been off the drug for just over a year and the itch/rash continued. A month ago I started Singulair, a leukotriene inhibitor, and the relief is substantially better. Results were seen after 2-3 days. Singulair is not a steroid. Its primary use is in asthma. Check with your doctors.
I had been on Opdivo for 2 yaers. Treatment is now over. Scans all look good. Never had chemo., went straight to Opdiivo. Had gone to Houston TX for operation by Dr. Sugerbaker, leader in mesothilioma treatment. Op was aborted, tumer too close to heart. However the Opdivo had a positive affect on the biopsies taken during he Op. Had many side affects bit weathered them all. Now being closely watched /fingers crossed.