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Regimen Information

For BTD, including Side Effects


Drugs in this Regimen:

For the treatment of Multiple Myeloma

How BTD chemotherapy is given and possible side effects.

BTD for the treatment of Multiple Myeloma

BTD is the acronym for a chemotherapy regimen used in the treatment of multiple myeloma

B = Velcade (bortezomib)

T = Thalomid (thalidomide)

D = dexamethasone

Chemotherapy is often given as a combination of drugs. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.


  • Nausea & Vomiting

  • Diarrhea

  • Constipation

  • Neuropathy

For more information, see the 'Expert Resources' tab below.

Community Responses

Often, the most helpful information regarding treatment side effects comes not from clinical brochures, but rather from other patients like you. We've collected the most helpful community resources to help you prepare for the side effects and coping tips for your chemotherapy regimen.

What side effects did you experience while on this medication?

Just call me Gordy.

I’ve had 4 cycles of revlimid, velcade and dexamethasone now. I guess the main side effect is neuropathy in my feet and fingertips. In my feet it is centered where my toes are connected, i.e., the balls. The sensitivity seems to worsen with each cycle. I didn’t experience anything else of consequence until the 4th cycle. I had diarrhea for a day and a half, not necessarily bad but annoying at best, The other thing that is really annoying is my feeling cold all the time, especially my feet. I have ordered some heated socks and am currently wearing thermal underwear.

  • Wed Nov 1, 2017

This discussion needs your voice!

What were the specific side effects that you experienced while taking this medication? How did you manage them?

What coping tips would you give to new patients on this regimen?

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This discussion needs your voice!

What do you wish you had known before taking this medication? What information would you like to pass on to patients who are beginning this medication?

Treatment Overview

This chemotherapy regimen is commonly used to treat:

Other chemotherapy regimens for the treatment of Multiple Myeloma:

See Expert Resources

The Navigating Care Library includes articles about cancer, chemotherapy regimens and drugs from the the National Cancer Institute and other experts.